Inhoudsopgave
Hoeveel uur werkt Duloxetine?
Kinetische gegevens
| F | 32–80% (gem. 50%). |
|---|---|
| T max | 6 uur, bij inname met voedsel 10 uur. |
| V d | 23,4 l/kg. |
| Eiwitbinding | ca. 96%. |
| Metabolisering | Uitgebreid in de lever via CYP1A2 en CYP2D6 tot inactieve metabolieten. |
Welke dosering Duloxetine?
Duloxetine wordt meestal eenmaal daags voorgeschreven. De startdosering is gewoonlijk 60 mg. Afhankelijk van het effect en de bijwerkingen kan dit opgehoogd worden naar maximaal 120 mg/dag. Het kan enkele weken duren voor een pijnstillend effect optreedt.
What is duloxetine?
What is duloxetine? Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI). Duloxetine affects chemicals in the brain that may be unbalanced in people with depression. Duloxetine is used to treat major depressive disorder in adults.
How long do the side effects of duloxetine last?
These side effects are usually mild and go away after a couple of weeks. If you and your doctor decide to take you off duloxetine, your doctor may recommend reducing your dose gradually to help prevent extra side effects. Duloxetine is also called by the brand names Cymbalta and Yentreve.
How do you take duloxetine for anxiety?
How and when to take it. For depression, anxiety and nerve pain, you’ll usually take duloxetine once a day. For urinary incontinence, you’ll usually take duloxetine twice a day. Swallow the capsules whole with a drink of water or juice.
Can you take duloxetine with food?
You can take duloxetine with or without food, but it’s best to take it at the same time each day. For depression, anxiety and nerve pain, duloxetine comes in 30mg and 60mg capsules. For stress urinary incontinence, duloxetine comes in 20mg and 40mg capsules.